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Prognostic assessment in COPD patients: BODE index and the health-related quality of life
Kapil Sharma1, Avinash Jain2, Rajendra Takhar3, DPS Sudan2, Vipin Goyal1, Nikhil Goel4, Vikram Singh5
1 Department of Chest and Tuberculosis, SHKM Govt. Medical College, Mewat, India
2 Department of Pulmonary Medicine, SGT Medical College, Gurgaon, Haryana, India
3 Department of Respiratory Medicine, Government Medical College, Kota, Rajasthan, India
4 Department of Psychiatry, SHKM Govt. Medical College, Mewat, Haryana, India
5 Department of Medicine, SHKM Govt. Medical College, Mewat, Haryana, India
Correspondence Address:
Dr. Kapil Sharma
Dept. of Chest and TB, Room no. 701, B 1 Block, Medical Campus, SHKM Govt. Medical College, Nalhar, Nuh, Mewat, Haryana, PIN-122107
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jacp.jacp_31_19
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Background: Chronic obstructive pulmonary disease (COPD) is a spreading epidemic of a debilitating disease impairing the health-related quality of life (HRQoL) of the patients. This study was conducted to identify the relationship between BODE (body mass index, obstruction, dyspnea, exercise capacity) index and the St George’s Respiratory Questionnaire (SGRQ) and to test the predictive value of both tools against survival. Methods: Open cohort study of 120 COPD patients were followed up to 1 year. At the time of the inclusion, clinical data, forced spirometry, 6-minute walking distance, BODE index, and SGRQ were determined. Vital status and cause of death were documented at the end of follow-up. Results: The cohort’s mean score of age, SGRQ Total (SGRQ_Tot), and BODE index was 57.82 ± 7.58, 44.77 ± 13.81, and 3.04 ± 2.06, respectively. The correlation between SGRQ_Tot and BODE index was good (r = 0.611, P < 0.001). Regression analysis determined age, BODE, comorbidity index, and activity component of SGRQ (SGRQ_A) as predictors of mortality. The area under the curve for the BODE index was 0.801 vs. 0.692 for the SGRQ_A score indicating BODE score as best predictor of mortality. The best cut-off value for predicting mortality was 4.5 for BODE index and 62.5 for SGRQ_A score. Conclusion: Evaluation of HRQoL is an important entity for improving overall disease outcome of COPD.
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