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Year : 2020  |  Volume : 8  |  Issue : 2  |  Page : 39-41

COVID 19-lung interactions: the salient points for pulmonologist


1 Woodlands Multispeciality Hospital, Kolkata, West Bengal, India
2 Department of Anatomy, College of Medicine & Sagore Datta Hospital, Kamarhati, Kolkata, West Bengal, India

Correspondence Address:
Dr. Arup Halder
MD (TB & Respiratory Diseases), Consultant Pulmonologist, 1/16/2, Manick Tala Main Road, Kolkata 700054, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jacp.jacp_40_20

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The COVID 19 virus gains entry into body by docking to ACE2 receptors of lungs. Subsequently it deranges the balance in RAS and destabilizes oxidant-antioxidant systems. It leads to cytokine storm and endothelial dysfunction. Intially lung is compliant but patients may be hypoxic due to vasoplegia. Later typical full blown ARDS set in.


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